There is a despicable trend that is becoming more and more common where the browser settings of web surfers are being forcibly hijacked by malicious web sites and software which modifies your default start and search pages. The purpose of this is force you to visit a web site of the hijacker's choice so that they can artificially inflate their web site's traffic for higher advertising revenues. Once hijacked, there is no simple answer because several different techniques are used. However, this website provides comprehensive advice on how to completely remove most hijackers.
http://www.spywareinfo.com/articles/hijacked/